1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-fluoro-3-nitrophenyl)urea CAS 1023474-24-9
| CAS No. | 1023474-24-9 |
| Molecular Formula | C25H23FN4O5 |
| Molecular Weight | 478.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-fluoro-3-nitrophenyl)urea is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-fluoro-3-nitrophenyl)urea (CAS 1023474-24-9), a certified reference material (molecular formula C25H23FN4O5, MW 478.47 g/mol) for analytical method development and quality control.
Based on its molecular formula C25H23FN4O5, 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-fluoro-3-nitrophenyl)urea contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 478.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H23FN4O5 |
| Molecular Weight | 478.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Dimethoxy Standards
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-fluoro-5-nitrophenyl)urea (CAS 1022665-81-1)
- 8,9-Dimethoxy-3-(propan-2-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1024020-20-9)
- 8,9-Dimethoxy-3-(propan-2-yl)-5-({[2-(trifluoromethyl)phenyl]methyl}sulfanyl)-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1030881-50-5)
- 6,7-Dimethoxy-3-octyl-2-((2,4,6-trimethylbenzyl)thio)quinazolin-4(3H)-imine (CAS 860789-49-7)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-methyl-4-nitrophenyl)urea (CAS 1023409-81-5)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-methyl-3-nitrophenyl)urea (CAS 1024435-80-0)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-methyl-2-nitrophenyl)urea (CAS 1024474-23-4)
- 2,6-Dimethoxy-N-(3-(2-methylpentadecan-2-yl)isoxazol-5-yl)benzamide (CAS 82558-67-6)
Recommended Standards
- Phenyl bis(4-phenylphenyl) phosphate (CAS 17270-00-7)
- Pralatrexate Impurity 3 (CAS CATO-C4X-22143)
- 3’,5’-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2’-O-methyluridine (CAS 869355-32-8)
- Enzalutamide Impurity 10 (CAS 1443331-78-9)
- 2-Methyl-1,2,3,4-tetrahydroquinoline (CAS 1780-19-4)
- 4-(3-(Methylsulfonyl)phenyl)piperidine (CAS 346688-72-0)
- 2-Morpholino-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid (CAS 1172951-03-9)
- (2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)(4-(hydroxymethyl)piperidin-1-yl)methanone (CAS 1179187-11-1)
- Imidazo[1,2-b]pyridazin-3-amine hydrochloride (CAS 159045-54-2)
- 3-(4-Chlorophenyl)-2-(phenylsulfonamido)propanoic acid (CAS 1214050-43-7)
- Methyl 3-(benzyloxy)-5-chlorothiophene-2-carboxylate (CAS 1707581-47-2)
- 1-(tert-Butyl)-3-(2-(furan-2-yl)-2-(indolin-1-yl)ethyl)urea (CAS 898458-06-5)
- 6-Methoxy-N-methylpyridine-2-carboxamide (CAS 1356543-02-6)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
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