8,9-Dimethoxy-3-(propan-2-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-2H,3H-imidazo[1,2-c]quinazolin-2-one CAS 1024020-20-9
| CAS No. | 1024020-20-9 |
| Molecular Formula | C23H22F3N3O3S |
| Molecular Weight | 477.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8,9-Dimethoxy-3-(propan-2-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-2H,3H-imidazo[1,2-c]quinazolin-2-one is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 8,9-Dimethoxy-3-(propan-2-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1024020-20-9), a certified reference material (molecular formula C23H22F3N3O3S, MW 477.50 g/mol) for analytical method development and quality control.
The molecular framework of 8,9-Dimethoxy-3-(propan-2-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-2H,3H-imidazo[1,2-c]quinazolin-2-one (C23H22F3N3O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8,9-Dimethoxy-3-(propan-2-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-2H,3H-imidazo[1,2-c]quinazolin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H22F3N3O3S |
| Molecular Weight | 477.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dimethoxy Standards
- 8,9-Dimethoxy-3-(propan-2-yl)-5-({[2-(trifluoromethyl)phenyl]methyl}sulfanyl)-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1030881-50-5)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-fluoro-5-nitrophenyl)urea (CAS 1022665-81-1)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-fluoro-3-nitrophenyl)urea (CAS 1023474-24-9)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-methyl-4-nitrophenyl)urea (CAS 1023409-81-5)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-methyl-3-nitrophenyl)urea (CAS 1024435-80-0)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-methyl-2-nitrophenyl)urea (CAS 1024474-23-4)
- 6,7-Dimethoxy-3-octyl-2-((2,4,6-trimethylbenzyl)thio)quinazolin-4(3H)-imine (CAS 860789-49-7)
- 2,6-Dimethoxy-N-(3-(2-methylpentadecan-2-yl)isoxazol-5-yl)benzamide (CAS 82558-67-6)
Recommended Standards
- Azlocillin Oxide Impurity (CAS CATO-C4X-23201)
- 3-Isopropyl-8,9-dimethoxy-5-((3-(trifluoromethyl)benzyl)thio)imidazo[1,2-c]quinazolin-2(3H)-one (CAS 1024595-16-1)
- Deacetylated cefotaxime (CAS CATO-C4X-12508)
- Mesityldiphenylphosphine (CAS 5931-56-6)
- 4,6-Dimethyl-1-(pentan-2-yl)-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-one (CAS 573939-28-3)
- Methyl 2-(2,3-dimethylphenyl)-2-oxoacetate (CAS 1314903-56-4)
- 2-Bromo-4-chloronicotinaldehyde (CAS 1289197-78-9)
- 4-[2-(chloromethyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]morpholine (CAS 99839-96-0)
- 4-Chloropyridine-2,6-dicarbohydrazide (CAS 98276-29-0)
- 4-(3-Chloro-4-fluorophenyl)-1,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazin-2-amine (CAS 1256628-16-6)
- 4-Amino-1-(3-fluorophenyl)pyrimidin-2(1H)-one (CAS 1416440-51-1)
- 9-Hydroxyetizolam (CAS 52170-72-6)
- (-)-Homoeriodictyol (CAS 446-71-9)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
Why CATO?
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