Resmetirom Impurity 47 CAS CATO-C4X-291247
| CAS No. | CATO-C4X-291247 |
| Molecular Formula | C20H17Cl2N3O3 |
| Molecular Weight | 418.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Resmetirom Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Resmetirom Impurity 47 (CAS CATO-C4X-291247) is a certified pharmaceutical impurity reference standard with the molecular formula C20H17Cl2N3O3 and a molecular weight of 418.27 g/mol.
Resmetirom Impurity 47 (C20H17Cl2N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H17Cl2N3O3 |
| Molecular Weight | 418.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Resmetirom Standards
- Resmetirom impurity 18 (CAS 1581304-52-0)
- Resmetirom Impurity 25 (CAS CATO-C4X-291225)
- Resmetirom Impurity 13 (CAS CATO-C4X-291213)
- Resmetirom Impurity 46 (CAS CATO-C4X-291246)
- Resmetirom Impurity 21 (CAS 920509-34-8)
- Resmetirom impurity 136 (CAS CATO-C4X-2912136)
- Resmetirom Impurity 24 (CAS 2987937-25-5)
- Resmetirom impurity 90 (CAS CATO-C4X-291290)
Recommended Standards
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- Mirabegron Impurity 36 (CAS 1684452-88-7)
- N-Nitroso Dexchlorpheniramine impurity 9 (CAS CATO-C4X-16119)
- Levonorgestrel EP Impurity A (CAS 1260525-53-8)
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- 4-Chloro-1-methyl-1H-pyrazole-3-carbonyl chloride (CAS 1048340-09-5)
- 2-((2,5-Dimethylbenzyl)thio)-3-ethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 587002-88-8)
- 5-(3,5-Dichlorophenyl)furan-2-carbaldehyde (CAS 106827-27-4)
- Copper(II) Tungsten Oxide (Metals Basis) (CAS 13587-35-4)
- N-Cyclohexyl-2-((2-oxo-2-((3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)amino)ethyl)thio)acetamide (CAS 851717-41-4)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com