11-(3,5-Dibromo-4-hydroxyphenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one CAS 1024228-08-7
| CAS No. | 1024228-08-7 |
| Molecular Formula | C21H20Br2N2O2 |
| Molecular Weight | 492.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 11-(3,5-Dibromo-4-hydroxyphenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
11-(3,5-Dibromo-4-hydroxyphenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 1024228-08-7), molecular formula C21H20Br2N2O2 and molecular weight 492.20 g/mol, is a CATO reference standard with documented purity and traceability.
11-(3,5-Dibromo-4-hydroxyphenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (C21H20Br2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 11-(3,5-Dibromo-4-hydroxyphenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H20Br2N2O2 |
| Molecular Weight | 492.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 3-(2,5-Dimethylphenyl)-1,2,4-oxadiazole-5-carbaldehyde (CAS 1708168-37-9)
- (Z)-N-((2-Amino-6,7-dihydrothiazolo[5,4-c]pyridin-5(4H)-yl)(methylimino)methyl)benzamide (CAS 97817-38-4)
- 3′-thymidylic acid, 5′-(dihydrogen phosphate) (CAS 2863-04-9)
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- 1-Bromo-5-chloroisoquinoline (CAS 1207448-41-6)
- Galactose 1-phosphate Potassium salt (CAS 19046-60-7)
- 2-Chloro-1-(2,2-dimethyl-2,3-dihydro-4H-benzo[b][1,4]thiazin-4-yl)ethan-1-one (CAS 591221-63-5)
- 3-Chloroacrylamide (CAS 52039-21-1)
- Naphtho[2,3-b]oxirene-2,7(1aH,7aH)-dione (CAS 15448-58-5)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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