2-[(E)-(4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenyl)methylidene]-1-hydrazinecarboxamide CAS 1025634-84-7
| CAS No. | 1025634-84-7 |
| Molecular Formula | C14H10ClF3N4O2 |
| Molecular Weight | 358.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[(E)-(4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenyl)methylidene]-1-hydrazinecarboxamide (CAS 1025634-84-7) is a high-purity analytical reference standard with the molecular formula C14H10ClF3N4O2 and a molecular weight of 358.70 g/mol.
The molecular framework of 2-[(E)-(4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenyl)methylidene]-1-hydrazinecarboxamide (C14H10ClF3N4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-[(E)-(4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenyl)methylidene]-1-hydrazinecarboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10ClF3N4O2 |
| Molecular Weight | 358.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- 3-Amino-1H-pyrazolo[4,3-b]pyridine-5-carbonitrile (CAS 1314979-27-5)
- 3-{imidazo[1,2-a]pyrimidin-2-yl}propanoic acid (CAS 956101-01-2)
- Ethyl 1-(4-(3,4-dichlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 956961-73-2)
- (3R,8AS)-3-methyloctahydropyrrolo[1,2-a]pyrazine (CAS 740787-48-8)
- 5-(Heptan-3-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1343610-62-7)
- 3-Allylnaphtho[2,1-d]thiazol-2(3H)-imine hydrobromide (CAS 1820587-66-3)
- 2-Hydrazinyl-4-methyl-6-(1H-pyrazol-1-yl)pyrimidine (CAS 1537190-57-0)
- 2-Amino-N-ethyl-N-(4-methylbenzyl)acetamide (CAS 1353948-26-1)
- 1-(2,7-Dichloroquinolin-3-yl)ethanone (CAS 1017403-35-8)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
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