1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-7'-fluoro-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole] CAS 1025905-33-2
| CAS No. | 1025905-33-2 |
| Molecular Formula | C21H19ClF4N4 |
| Molecular Weight | 438.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-7'-fluoro-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole] (CAS 1025905-33-2), molecular formula C21H19ClF4N4 and molecular weight 438.85 g/mol, is a CATO reference standard with documented purity and traceability.
1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-7'-fluoro-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole] (C21H19ClF4N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-7'-fluoro-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole] under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19ClF4N4 |
| Molecular Weight | 438.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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- 2-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethyl)-2,3-dihydro-1H-isoindole-1,3-dione (CAS 338761-86-7)
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Recommended Standards
- {2-[(2-chlorophenyl)sulfanyl]pyridin-3-yl}methyl N-[3-(trifluoromethyl)phenyl]carbamate (CAS 339278-60-3)
- Bmt-145027 (CAS 2018282-44-3)
- Chloroacetamido-PEG4-NHS ester (CAS 1353011-95-6)
- Amlodipine Impurity 84 (CAS 906098-03-1)
- N-(4-bromophenyl)-1-methyl-1H-pyrazole-4-carboxamide (CAS 1015529-65-3)
- Levomedetomidine (CAS 119717-21-4)
- 2-((1-(2-Chlorobenzyl)-1H-imidazol-2-yl)thio)-N-cyclohexylacetamide (CAS 946202-78-4)
- 2-cyclobutyl-1,3-oxazole-4-carbonitrile (CAS 1190314-22-7)
- Ethyl (2Z)-2-chloro-2-[2-(2,5-dichlorophenyl)hydrazin-1-ylidene]acetate (CAS 1264088-37-0)
- (3-Mercaptophenyl)methanol (CAS 83794-86-9)
- 3-Amino-1-phenylpyridin-2(1H)-one (CAS 1614217-70-7)
- 2-((5-(Methylthio)-1,3,4-thiadiazol-2-yl)thio)-1-(1h-pyrrol-2-yl)ethan-1-one (CAS 876680-31-8)
- 2-(2,4-Dioxo-1,3-diazaspiro[4.5]decan-3-yl)-N-(4-methylbenzyl)acetamide (CAS 781619-57-6)
- Tau Peptide (306-317) trifluoroacetate salt (CAS 1003007-59-7)
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