(E)-6-chloro-4-(methylsulfonyl)-N'-(4-nitrobenzylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carbohydrazide CAS 866134-94-3
| CAS No. | 866134-94-3 |
| Molecular Formula | C17H15ClN4O6S |
| Molecular Weight | 438.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-6-chloro-4-(methylsulfonyl)-N'-(4-nitrobenzylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carbohydrazide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-6-chloro-4-(methylsulfonyl)-N'-(4-nitrobenzylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carbohydrazide (CAS 866134-94-3) is a high-purity analytical reference standard with the molecular formula C17H15ClN4O6S and a molecular weight of 438.84 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, (E)-6-chloro-4-(methylsulfonyl)-N'-(4-nitrobenzylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carbohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 438.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-6-chloro-4-(methylsulfonyl)-N'-(4-nitrobenzylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15ClN4O6S |
| Molecular Weight | 438.84 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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