(2E)-1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-3-(dimethylamino)prop-2-en-1-one CAS 1164529-81-0
| CAS No. | 1164529-81-0 |
| Molecular Formula | C21H22ClF3N4O |
| Molecular Weight | 438.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2E)-1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-3-(dimethylamino)prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2E)-1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-3-(dimethylamino)prop-2-en-1-one (CAS 1164529-81-0) is a high-purity analytical reference standard with the molecular formula C21H22ClF3N4O and a molecular weight of 438.87 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (2E)-1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-3-(dimethylamino)prop-2-en-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 438.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H22ClF3N4O |
| Molecular Weight | 438.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- 2'-chloro-6'-fluoro-5-hydroxy-4-(1,2,3,4-tetrahydroisoquinolin-1-yl)-6-(1H-1,2,4-triazol-1-yl)-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 1005119-26-5)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338412-98-9)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-7'-fluoro-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole] (CAS 1025905-33-2)
- N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}phenyl)-4-methoxybenzamide (CAS 338773-32-3)
- 4-Chloro-1-trityl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (CAS 2448475-28-1)
- (E)-6-chloro-4-(methylsulfonyl)-N'-(4-nitrobenzylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carbohydrazide (CAS 866134-94-3)
- 3-(N-(2-(2-Chloro-4-nitrophenoxy)ethyl)sulfamoyl)benzene-1-sulfonyl fluoride (CAS 25240-50-0)
- 2-((5-Chloro-2-((4-morpholinophenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide (CAS 1042432-58-5)
Recommended Standards
- Finerenone Impurity 285 (CAS CATO-C4X-2880285)
- Hydroxy-Bifenthrin (CAS 146726-17-2)
- Amlodipine Impurity 84 (CAS 906098-03-1)
- Chloroacetamido-PEG4-NHS ester (CAS 1353011-95-6)
- H-p-Bromo-Phe-OH (CAS 24250-84-8)
- Chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium(II) 32993-05-8 BIS(TRIPHENYLPHOSPHINE)(CHLORO)CYCLOPENTADIENYLRUTHENIUM;BIS(TRIPHENYLPHOSPHINE)CYCLOPENTADIENYLRUTHENIUM CHLORIDE;CHLOROCYCLOPENTADIENYLBIS(TRIPHENYLPHOSPHINE)RUTHENIUM(II);CYCLOPENTADIENYL RUTHENIUM CHLORIDE BIS-(TRIPHENYLPHOSPHIN) COMPLEX;CYCLOPENTADIENYLBIS(TRIPHENYLPHOSPHINE)RUTHENIUM CHLORIDE;CYCLOPENTADIENYLBIS(TRIPHENYLPHOSPHINE)RUTHENIUM(II) CHLORIDE;Chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium(II) SC10200 (CAS 32993-05-8)
- 6,7-Difluoro-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 1269531-40-9)
- 5-Methyl-N-(3-phenylpropyl)furo[3,2-b]pyridine-2-carboxamide (CAS 941969-23-9)
- Tetrahydro-11-deoxy Cortisol 3-O-beta-D-Glucuronide (CAS 56162-40-4)
- Isobutylamine Hydrobromide (CAS 74098-36-5)
- (2S,3S)-3-amino-2-((carbamoyloxy)methyl)-4-oxoazetidine-1-sulfonic acid (CAS 88852-06-6)
- Pentamidine (CAS 100-33-4)
- Minocycline impurity 73 (CAS 156263-28-4)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com