(E)-4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-ylidene)quinolin-2(3H)-one CAS 1027263-12-2
| CAS No. | 1027263-12-2 |
| Molecular Formula | C21H21FN6O |
| Molecular Weight | 392.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (E)-4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-ylidene)quinolin-2(3H)-one (CAS 1027263-12-2), a certified reference material (molecular formula C21H21FN6O, MW 392.43 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (E)-4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-ylidene)quinolin-2(3H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 392.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H21FN6O |
| Molecular Weight | 392.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related E Standards
- 3-Amino-7-methyl-N-(2-methyl-4-nitrophenyl)thieno[2,3-b]quinoline-2-carboxamide (CAS 332885-30-0)
- 4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one 804551-71-1 CHIR-258 Chir 258 D07OZR TKI-258 TKI-258, Dovitinib, CHIR258, TKI258 TKI258 (CAS 804551-71-1)
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Recommended Standards
- 2-((6-(4-(1H-Pyrazol-1-yl)phenyl)pyridazin-3-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide (CAS 1004439-73-9)
- (3-Fluorophenyl)(4-(6-(4-methoxyphenyl)pyridazin-3-yl)piperazin-1-yl)methanone (CAS 1040639-38-0)
- Flumetasone Impurity 18 (CAS CATO-C4X-191018)
- Benzo[c][1,2,5]thiadiazol-5-yl(4-(6-(furan-2-yl)pyridazin-3-yl)piperazin-1-yl)methanone (CAS 1203201-94-8)
- Ethyl 2,2-dimethyl-4-(4-methoxyphenyl)-4-oxobutyrate (CAS 898753-56-5)
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- (2E)-2-[(Cyanomethoxy)imino]-N-(2,4-difluorophenyl)acetamide (CAS 866043-48-3)
- 4-Benzyl-N-methylmorpholine-2-carboxamide (CAS 135072-16-1)
- (1R,4aS,7aS)-Methyl 1-(benzyloxy)-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (CAS 206755-40-0)
- (Z)-4-((5-Methylthiophen-2-yl)methylene)-2-phenyloxazol-5(4H)-one (CAS 88991-49-5)
- 2-3-5-Tri-O-benzyl-D-arabino-1-4-lactone (CAS 14233-64-8)
- (S)-tert-Butyl 2-(piperidin-4-yl)pyrrolidine-1-carboxylate (CAS 1449131-15-0)
- Semaglutide impurity 73 (CAS CATO-C4X-222673)
Why CATO?
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