2-(3-(3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl)-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl)-N-(thiophen-2-ylmethyl)acetamide CAS 1029770-32-8
| CAS No. | 1029770-32-8 |
| Molecular Formula | C24H18FN5O3S |
| Molecular Weight | 475.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 475.49 g/mol gives 2-(3-(3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl)-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl)-N-(thiophen-2-ylmethyl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(3-(3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl)-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl)-N-(thiophen-2-ylmethyl)acetamide (CAS 1029770-32-8), molecular formula C24H18FN5O3S and molecular weight 475.49 g/mol, is a CATO reference standard with documented purity and traceability.
2-(3-(3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl)-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl)-N-(thiophen-2-ylmethyl)acetamide (C24H18FN5O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H18FN5O3S |
| Molecular Weight | 475.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 3-Benzyl-5-{[(2-fluorophenyl)methyl]sulfanyl}-8,9-dimethoxy-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 477768-45-9)
- 8-((4-Fluorophenyl)sulfonyl)-2-(4-methoxyphenyl)-3-(propylthio)-1,4,8-triazaspiro[4.5]deca-1,3-diene (CAS 932549-54-7)
- N-[(4-Fluorophenyl)methyl]-1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321848-22-0)
- 5-Benzyl-3-{4-[(4-fluorophenyl)methoxy]-3-methoxyphenyl}-2-methyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 317821-81-1)
- 2-{[(4-fluorophenyl)methyl]sulfanyl}-6-[(E)-2-(4-methylphenyl)ethenyl]-4-[(Z)-2-(4-methylphenyl)ethenyl]pyridine-3-carbonitrile (CAS 303985-29-7)
- Ethyl 2-(4-fluorophenyl)-6-nitro-5-(((trifluoromethyl)sulfonyl)oxy)benzofuran-3-carboxylate (CAS 691857-51-9)
- Ethyl 7-(4-fluorophenyl)-2-methyl-5-oxo-4-(2-(trifluoromethyl)phenyl)-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 338414-99-6)
- 2-(4-Fluorophenyl)-1-(2-((3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)amino)-6,7-dihydrothiazolo[5,4-c]pyridin-5(4H)-yl)ethanone (CAS 1077629-25-4)
Recommended Standards
- Samidorphan Impurity 8 (CAS CATO-C4X-33098)
- 2-((4-(N-(4-sulfamoylphenyl)sulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 396135-06-1)
- Tenofovir disoproxil Impurity 141 (CAS CATO-C4X-1076141)
- 2-(4-(2-Amino-3-cyano-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2-methoxyphenoxy)-N-(2-methoxyphenyl)acetamide (CAS 333417-69-9)
- (S)-3-Amino-3-(4-bromothiophen-2-yl)propanamide (CAS 1306166-18-6)
- 2-Benzamido-N-(2-hydroxyethyl)-4-phenylthiophene-3-carboxamide (CAS 446831-15-8)
- (R)-3-(4-Acetamidophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 1213917-89-5)
- Ethyl 4-chlorocinnoline-3-carboxylate (CAS 860776-85-8)
- Ethyl 2-methylpiperidine-2-carboxylate (CAS 66937-98-2)
- 3-(Azepan-1-ylmethyl)-6-fluoro-1H-indole (CAS 1893730-27-2)
- rac-2-[(1R,2S)-2-phenylcyclopropyl]acetonitrile (CAS 1821769-92-9)
- O-(2-Nitrobenzyl)-L-tyrosine (CAS 184591-51-3)
- 1-Benzyl-6-chloro-1H-benzo[c][1,2]thiazin-4(3H)-one 2,2-dioxide (CAS 1255783-37-9)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com