N-[(4-Fluorophenyl)methyl]-1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide CAS 321848-22-0
| CAS No. | 321848-22-0 |
| Molecular Formula | C22H16F4N4O2S |
| Molecular Weight | 476.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-[(4-Fluorophenyl)methyl]-1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide.
N-[(4-Fluorophenyl)methyl]-1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321848-22-0) is a high-purity analytical reference standard with the molecular formula C22H16F4N4O2S and a molecular weight of 476.45 g/mol.
Based on its molecular formula C22H16F4N4O2S, N-[(4-Fluorophenyl)methyl]-1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 476.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16F4N4O2S |
| Molecular Weight | 476.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
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- 2-(4-Fluorophenyl)-1-(2-((3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)amino)-6,7-dihydrothiazolo[5,4-c]pyridin-5(4H)-yl)ethanone (CAS 1077629-25-4)
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Recommended Standards
- N-(9-Phenyl-9H-selenoxanthen-9-yl)benzenesulfonamide (CAS 82238-30-0)
- Travoprost Impurity 15 (CAS 208111-99-3)
- Methyl 4-(3-(3-fluoro-4-methoxybenzoyl)-4-hydroxy-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-pyrrol-2-yl)benzoate (CAS 618074-85-4)
- Travoprost Impurity 17 (CAS 208114-58-3)
- 3-Chloro-2-(pyrrolidin-1-yl)pyridine (CAS 1289079-66-8)
- 4-(Trifluoromethyl)benzo[b]thiophene (CAS 120568-06-1)
- 2-Methyl-N-(1-(thiophen-2-yl)ethyl)aniline (CAS 1020989-45-0)
- 3-Methoxy-4-(trifluoromethyl)benzaldehyde (CAS 945003-38-3)
- 1-[(2R,3S)-4-[(4-Chloro-1,1,2,2,3,3,4,4-octafluorobutyl)sulfonyl]-5-methyl-3-(4-nitrophenyl)-2,3-dihydro-2-furanyl]ethanone (CAS 771491-74-8)
- 4-(2,6-Dichloro-4-(trifluoromethyl)phenoxy)aniline (CAS 61946-83-6)
- 1-(Cyano(thiophen-2-yl)methyl)piperidine-4-carboxylic acid (CAS 1018244-80-8)
- 3,3-Dimethyl-4-phenylpyrrolidine (CAS 1423117-62-7)
- 1-(3-Chloro-4-methoxyphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1416344-94-9)
- Neuropeptide W-23 (human) (CAS 383415-79-0)
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