Entecavir Impurity 19 CAS 1030919-51-7
| CAS No. | 1030919-51-7 |
| Molecular Formula | C19H21N5O3 |
| Molecular Weight | 367.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Entecavir Impurity 19 (CAS 1030919-51-7) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21N5O3 and a molecular weight of 367.40 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Entecavir Impurity 19 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 367.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Entecavir Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21N5O3 |
| Molecular Weight | 367.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 5 |
Related Entecavir Standards
- Entecavir Impurity 75 (CAS 701278-13-9)
- Entecavir Impurity 27 (CAS CATO-C4X-107727)
- Entecavir Impurity 28 (CAS CATO-C4X-107728)
- Entecavir Impurity 29 (CAS CATO-C4X-107729)
- Entecavir Impurity 30 (CAS CATO-C4X-107730)
- Entecavir-(R)-Methylethyl Carboxylic Acid (CAS 1415118-53-4)
- Entecavir-(S)-Methylethyl Carboxylic Acid (CAS 1415118-52-3)
- Entecavir Impurity 44 (CAS 1354715-30-2)
Recommended Standards
- tert-Butyl (3-(benzyloxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-8-yl)carbamate (CAS 2304495-86-9)
- N-Fmoc-O-cyclopropyl-L-serine (CAS 2642331-45-9)
- Alogliptin Impurity 14 (CAS CATO-C4X-109914)
- N-Allyl-2-imino-1-(2-methoxyethyl)-10-methyl-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide (CAS 371137-31-4)
- Palbociclib Impurity 146 (CAS 2955712-44-2)
- 2,2'-((2-((2-aminoethyl)amino)ethyl)azanediyl)diacetic acid (CAS 2276662-37-2)
- Cilastatin Impurity 44 (CAS CATO-C4X-196044)
- 5,6-Dichloro-2-cyclopropylnicotinonitrile (CAS 1779123-29-3)
- 3-(4-(Trifluoromethyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine (CAS 879072-54-5)
- 9-Chloroacridine (CAS 1207-69-8)
- Terbinafine Impurity 5-d7 (CAS 1185238-58-7)
- 1-(2-Methylimidazo[1,2-a]pyridin-3-yl)-2-(phenylthio)ethan-1-one (CAS 478029-65-1)
- (R)-2-amino-3-(4-fluoro-1H-indol-3-yl)propanoic acid (CAS 110221-04-0)
- TRAF6 Peptide trifluoroacetate salt (CAS 852805-92-6)
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