Hydroxychloroquine EP Impurity B CAS 103152-84-7
| CAS No. | 103152-84-7 |
| Molecular Formula | C18H26ClN3O4S |
| Molecular Weight | 415.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Hydroxychloroquine EP Impurity B (CAS 103152-84-7), a pharmacopoeial impurity reference standard (molecular formula C18H26ClN3O4S, MW 415.93 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H26ClN3O4S, Hydroxychloroquine EP Impurity B contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 415.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Hydroxychloroquine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H26ClN3O4S |
| Molecular Weight | 415.93 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine Impurity 30 (CAS CATO-C4X-183530)
- Hydroxychloroquine Impurity 41 (CAS CATO-C4X-183541)
- Hydroxychloroquine Impurity 42 (CAS CATO-C4X-183542)
- Hydroxychloroquine Impurity 44 (CAS CATO-C4X-183544)
- Hydroxychloroquine Impurity 40 (CAS CATO-C4X-183540)
- Hydroxychloroquine Impurity 37 (CAS CATO-C4X-183537)
- Hydroxychloroquine Impurity 31 (CAS CATO-C4X-183531)
- Hydroxychloroquine Impurity 7 (CAS 47493-14-1)
Recommended Standards
- Tetracosanoic-d47 Acid (CAS 68060-00-4)
- 3-Amino-N-(5-chloro-2-methoxyphenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 445268-99-5)
- 4-[(E)-2-(4-Chlorophenyl)ethenyl]-8-phenoxy-2H,3H-thieno[3,2-c]quinoline (CAS 865658-54-4)
- Ethyl 2-(4-(3-chlorophenyl)piperazin-1-yl)-5-(thiophen-2-yl)-1H-pyrrole-3-carboxylate (CAS 478050-20-3)
- Ceftolozane Impurity 42 (CAS CATO-C4X-240642)
- Aprepitant Impurity 80 (CAS CATO-C4X-114180)
- Sildenafil Impurity 306 (CAS CATO-C4X-1128306)
- (3-Chlorophenyl)(3-(methylamino)piperidin-1-yl)methanone hydrochloride (CAS 1840309-29-6)
- HIV-1 gag Protein p24 (65-73) (isolates MAL/U455) (H-6222.0001) (CAS 334731-59-8)
- DA5 (CAS 51717-52-3)
- 3,4-Dimethylpyrrolidine-1-carboxamide (CAS 90184-86-4)
- Azetidin-3-yl(pyridin-2-yl)methanol oxalate (CAS 1864063-64-8)
- tert-Butyl 4,4-dimethyl-3,4-dihydrobenzo[b][1,4]azasiline-1(2H)-carboxylate (CAS 1370735-24-2)
- Peptide 74 (H-8545.0500) (CAS 132116-39-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com