Hydroxychloroquine Impurity 44 CAS CATO-C4X-183544
| CAS No. | CATO-C4X-183544 |
| Molecular Formula | C20H30ClN3O4S |
| Molecular Weight | 443.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Hydroxychloroquine Impurity 44.
CATO supplies Hydroxychloroquine Impurity 44 (CAS CATO-C4X-183544), a pharmacopoeial impurity reference standard (molecular formula C20H30ClN3O4S, MW 443.99 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H30ClN3O4S, Hydroxychloroquine Impurity 44 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 443.99 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Hydroxychloroquine Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H30ClN3O4S |
| Molecular Weight | 443.99 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine Impurity 41 (CAS CATO-C4X-183541)
- Hydroxychloroquine Impurity 42 (CAS CATO-C4X-183542)
- Hydroxychloroquine Impurity 37 (CAS CATO-C4X-183537)
- Hydroxychloroquine impurity 82 (CAS CATO-C4X-183582)
- Hydroxychloroquine Impurity 30 (CAS CATO-C4X-183530)
- Hydroxychloroquine Impurity 39 (CAS CATO-C4X-183539)
- Hydroxychloroquine EP Impurity B (CAS 103152-84-7)
- Hydroxychloroquine Impurity 43 (CAS CATO-C4X-183543)
Recommended Standards
- 2-Amino-2-(4-((3-(benzyloxy)phenyl)thio)-2-chlorophenethyl)propane-1,3-diol (CAS 509092-16-4)
- (E)-3-(4-ethoxy-3,5-diiodophenyl)acrylic acid (CAS 938018-89-4)
- Ethyl 4-(4-chlorobenzoyl)-8-phenyl-1-thia-4-azaspiro[4.5]decane-3-carboxylate (CAS 1030920-60-5)
- Trichlorodocosylsilane (CAS 7325-84-0)
- Ascorbic Acid Impurity 2 (CAS CATO-C4X-31442)
- Cefotiam Impurity 36 (CAS 95761-91-4)
- Ursodeoxycholic Acid impurity 97 (CAS CATO-C4X-142297)
- 1-(4-Chlorophenyl)-3-(furan-2-ylmethyl)urea (CAS 6298-28-8)
- 3-Formyl-2,2,5,5-tetramethyl-1,3-thiazolidine-4-carboxylic Acid (CAS 55234-12-3)
- N-(4-Hydroxy-3-(pyrrolidin-1-ylmethyl)phenyl)acetamide (CAS 13886-02-7)
- 3-(1-(2-Cyanoethyl)-3,5-dimethyl-1H-pyrazol-4-yl)-N-(4-(morpholine-4-carbonyl)benzyl)propanamide (CAS 1171168-13-0)
- Ethyl 3-(N-(3-chloro-2-methylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate (CAS 932520-07-5)
- 2,3-Dimethoxy-6-fluorobenzyl alcohol (CAS 1260814-69-4)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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