Ceritinib Impurity 18 CAS CATO-C4X-104818
| CAS No. | CATO-C4X-104818 |
| Molecular Formula | C18H7Cl6N7S |
| Molecular Weight | 566.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Ceritinib Impurity 18 (CAS CATO-C4X-104818) is a certified pharmaceutical impurity reference standard with the molecular formula C18H7Cl6N7S and a molecular weight of 566.08 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, Ceritinib Impurity 18 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 566.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Ceritinib Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H7Cl6N7S |
| Molecular Weight | 566.08 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Ceritinib Standards
- Ceritinib (CAS 1032900-25-6)
- Ceritinib Impurity 64 (CAS CATO-C4X-104864)
- Ceritinib Impurity 68 (CAS CATO-C4X-104868)
- Ceritinib Impurity 69 (CAS CATO-C4X-104869)
- Ceritinib Impurity 10 (CAS CATO-C4X-104810)
- Ceritinib Impurity 66 (CAS CATO-C4X-104866)
- Ceritinib Impurity 74 (CAS CATO-C4X-104874)
- Ceritinib Impurity 8 (CAS CATO-C4X-10488)
Recommended Standards
- 400626-82-6 CTK4I2358 Cyclohexane,1,1,2,2,3,3,4,5,5,6-decafluoro-4-(1,1,2,2,3,3,3-heptafluoropropoxy)-6-(1,1,2,2,2-pentafluoroethyl)- (CAS 400626-82-6)
- 4-(3-Thioxo-3H-1,2-dithiol-5-yl)phenyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate (CAS 1000700-26-4)
- N,N-Diethyl-2-methyl-5-((4-(2-(4-(3-methylureido)phenyl)pyridin-4-yl)pyrimidin-2-yl)amino)benzenesulfonamide, >96% (CAS 1402452-15-6)
- UTPγS Trisodium SaltDISCONTINUED (CAS 1266569-94-1)
- Niraparib Impurity 43 (CAS CATO-C4X-232943)
- Tunodafil Impurity 4 HCl (CAS CATO-C4X-31104)
- Ponatinib Impurity 51 (CAS 94224-92-7)
- (S)-2-([2,2'-bipyridin]-6-yl)-4-isopropyl-4,5-dihydrooxazole (CAS 2634687-65-1)
- (6-Chloropyrazin-2-yl)glycine (CAS 1159822-45-3)
- 7-Isopropyl-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline (CAS 1268144-17-7)
- (1R,3S,5r,7r)-2-Aminoadamantane-2-carboxylic acid hydrochloride (CAS 50294-51-4)
- Ethyl (1E)-N-Hydroxyethanimidate (CAS 20703-41-7)
- 2-(Chloromethyl)-4-(difluoromethyl)pyridine-5-carboxylic acid (CAS 1805327-99-4)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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