Ceritinib Impurity 74 CAS CATO-C4X-104874
| CAS No. | CATO-C4X-104874 |
| Molecular Formula | C27H34ClN5O3S |
| Molecular Weight | 544.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ceritinib Impurity 74 (CAS CATO-C4X-104874), a pharmacopoeial impurity reference standard (molecular formula C27H34ClN5O3S, MW 544.11 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C27H34ClN5O3S, Ceritinib Impurity 74 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 544.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ceritinib Impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H34ClN5O3S |
| Molecular Weight | 544.11 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ceritinib Standards
- Ceritinib Impurity 8 (CAS CATO-C4X-10488)
- Ceritinib Impurity 27 (CAS CATO-C4X-104827)
- Ceritinib Impurity 11 (CAS CATO-C4X-104811)
- Ceritinib Impurity 12 (CAS CATO-C4X-104812)
- Ceritinib Impurity 10 (CAS CATO-C4X-104810)
- Ceritinib (CAS 1032900-25-6)
- Ceritinib Impurity 5 (CAS CATO-C4X-10485)
- Ceritinib Impurity 64 (CAS CATO-C4X-104864)
Recommended Standards
- Mono[2-(perfluorooctyl)ethyl] phosphate (CAS 57678-03-2)
- 2,4,6 Tris(4-bromophenyl)pyridine (CAS 21399-28-0)
- Amiodarone Impurity 48 (CAS CATO-C4X-142548)
- 2,4,6-Tris(3-bromophenyl)pyridine (CAS 1360743-16-3)
- Pentazocine Impurity 5 (CAS 18175-34-3)
- Selexipag Impurity 48 (CAS CATO-C4X-196148)
- Axitinib Impurity 52 (CAS CATO-C4X-107152)
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- 1-(5-Bromopyridin-2-yl)-1,4-diazepane (CAS 855787-68-7)
- tert-Butyl 2-((2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamido)methyl)piperidine-1-carboxylate (CAS 1353958-81-2)
- 5-Amino-2-(2H-1,2,3-triazol-2-yl)nicotinonitrile (CAS 2097854-16-3)
- 1-Phenyl-4-propoxy-1h-pyrazole-3-carboxylic acid (CAS 1152625-34-7)
- 3-Benzyl-1-(3,4-dimethoxyphenethyl)-4-hydroxypyridin-2(1H)-one (CAS 478247-71-1)
- Osteoblast Activating Peptide (mouse, rat) (H-7262.0500) (CAS 1222950-80-2)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com