3-(2-Bromophenyl)-5-(3-chlorophenyl)-1,2,4-oxadiazole CAS 1033201-83-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1033201-83-0
Molecular FormulaC14H8BrClN2O
Molecular Weight335.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2-Bromophenyl)-5-(3-chlorophenyl)-1,2,4-oxadiazole CAS 1033201-83-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(2-Bromophenyl)-5-(3-chlorophenyl)-1,2,4-oxadiazole.

CATO supplies 3-(2-Bromophenyl)-5-(3-chlorophenyl)-1,2,4-oxadiazole (CAS 1033201-83-0), a certified reference material (molecular formula C14H8BrClN2O, MW 335.58 g/mol) for analytical method development and quality control.

The molecular framework of 3-(2-Bromophenyl)-5-(3-chlorophenyl)-1,2,4-oxadiazole (C14H8BrClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H8BrClN2O
Molecular Weight335.58 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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