3-(2-Bromophenyl)-5-(4-chlorophenyl)-1,2,4-oxadiazole CAS 425373-64-4
| CAS No. | 425373-64-4 |
| Molecular Formula | C14H8BrClN2O |
| Molecular Weight | 335.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Bromophenyl)-5-(4-chlorophenyl)-1,2,4-oxadiazole (C14H8BrClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-(2-Bromophenyl)-5-(4-chlorophenyl)-1,2,4-oxadiazole (CAS 425373-64-4), molecular formula C14H8BrClN2O and molecular weight 335.58 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8BrClN2O |
| Molecular Weight | 335.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromophenyl Standards
- 3-(2-Bromophenyl)-5-(2-chlorophenyl)-1,2,4-oxadiazole (CAS 1000339-28-5)
- 3-(2-Bromophenyl)-5-(3-chlorophenyl)-1,2,4-oxadiazole (CAS 1033201-83-0)
- 3-(4-Bromophenyl)-5-(2-chlorophenyl)-1,2,4-oxadiazole (CAS 404900-69-2)
- 3-(4-Bromophenyl)-5-(4-chlorophenyl)-1,2,4-oxadiazole (CAS 489435-05-4)
- (4-Bromophenyl)[2-(4-chlorophenyl)cyclopropyl]methanone (CAS 338401-41-5)
- 1-(4-Bromophenyl)-4-pentylbicyclo[2.2.2]octane (CAS 76921-48-7)
- 1-(4-Bromophenyl)-3-(4-methylbenzyl)thiourea (CAS 133192-89-9)
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Recommended Standards
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