2-Bromo-2-(4-chlorophenyl)-1H-indene-1,3(2H)-dione CAS 730-73-4

Purity 97%+In StockPharmaceutical Standards
CAS No.730-73-4
Molecular FormulaC15H8BrClO2
Molecular Weight335.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-2-(4-chlorophenyl)-1H-indene-1,3(2H)-dione CAS 730-73-4 chemical structure

Description

The occurrence of 2-Bromo-2-(4-chlorophenyl)-1H-indene-1,3(2H)-dione is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-Bromo-2-(4-chlorophenyl)-1H-indene-1,3(2H)-dione (CAS 730-73-4), a certified reference material (molecular formula C15H8BrClO2, MW 335.58 g/mol) for analytical method development and quality control.

The molecular framework of 2-Bromo-2-(4-chlorophenyl)-1H-indene-1,3(2H)-dione (C15H8BrClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H8BrClO2
Molecular Weight335.58 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl/Br-containing

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