Dabrafenib Impurity 12 CAS CATO-C4X-303312
| CAS No. | CATO-C4X-303312 |
| Molecular Formula | C24H23F2N5O3S2 |
| Molecular Weight | 531.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dabrafenib Impurity 12 (C24H23F2N5O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Dabrafenib Impurity 12 (CAS CATO-C4X-303312) is a certified pharmaceutical impurity reference standard with the molecular formula C24H23F2N5O3S2 and a molecular weight of 531.60 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dabrafenib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23F2N5O3S2 |
| Molecular Weight | 531.60 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Dabrafenib Standards
- Dabrafenib Impurity 19 (CAS 1907654-22-1)
- Dabrafenib-D9 (CAS 1423119-98-5)
- Dabrafenib Impurity N2 (CAS 1195767-77-1)
- Dabrafenib Impurity 37 (CAS CATO-C4X-303337)
- Dabrafenib Impurity 38 (CAS 3052138-43-6)
- Dabrafenib Impurity 9 (CAS CATO-C4X-30339)
- Dabrafenib Impurity 24 (CAS CATO-C4X-303324)
- Dabrafenib Impurity N7 (CAS 1195768-23-0)
Recommended Standards
- Z-His(Trt)-OH (CAS 82882-71-1)
- Fmoc-Pro-Pro-Pro-OH (CAS 134303-96-1)
- n-(2'-(Diphenylphosphanyl)-[1,1'-binaphthalen]-2-yl)methanesulfonamide (CAS 278800-87-6)
- AZD-9291 Impurity 15 (CAS CATO-C4X-112715)
- Mirtazapine Impurity 2 (CAS CATO-C4X-15112)
- Dyclonine Impurity 13 (CAS 42528-76-7)
- Tedizolid Impurity 97 (CAS 885951-58-6)
- (S)-3-(3,5-Bis(trifluoromethyl)phenyl)piperazin-2-one (CAS 1240588-14-0)
- Diethylpent-4-enylamine (CAS 13173-21-2)
- tert-Butyl ((1-(2-aminoacetyl)piperidin-4-yl)methyl)(isopropyl)carbamate (CAS 1353953-12-4)
- 2-((1-(2-Fluorophenyl)-1H-tetrazol-5-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 562866-41-5)
- (1R,2S)-2-(2-(4-iodophenyl)-2-oxoethyl)cyclohexane-1-carboxylic acid (CAS 735274-97-2)
- (3R)-3-Amino-4,4-dimethylthietan-2-one (CAS 88199-78-4)
- TRAF6 Peptide trifluoroacetate salt (CAS 852805-92-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com