5-Fluoro-1-(4-hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione CAS 10343-71-2
| CAS No. | 10343-71-2 |
| Molecular Formula | C28H25FN2O5 |
| Molecular Weight | 488.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Fluoro-1-(4-hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione.
CATO supplies 5-Fluoro-1-(4-hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 10343-71-2), a certified reference material (molecular formula C28H25FN2O5, MW 488.51 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5-Fluoro-1-(4-hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 488.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H25FN2O5 |
| Molecular Weight | 488.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-(pentyloxy)phenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618076-13-4)
- 3-(6-Fluoro-1H-indol-3-yl)-2-(4-iodobenzenesulfonamido)propanoic acid (CAS 1796902-05-0)
- N-{2-[5-Fluoro-2-(pyridin-2-yl)-1H-indol-3-yl]ethyl}-4-phenoxybenzene-1-sulfonamide (CAS 1253527-96-6)
- (16beta)9-fluoro-16-methyl-17,21-bis(1-oxopropoxy)-Pregna-1,4,11-triene-3,20-dione (CAS 65669-64-9)
- 5-Fluoro-6-iodo-1-(triisopropylsilyl)-4-(trimethylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1261365-70-1)
- 6-Fluoro-8-(2,2,3,3,10,10,11,11-octamethyl-4,9-dioxa-3,10-disiladodecan-6-yl)isoquinoline-5-carbaldehyde (CAS 2842055-03-0)
- Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(2-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate (CAS 618072-60-9)
- Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(3-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate (CAS 618072-65-4)
Recommended Standards
- Flurbiprofen Impurity 107 (CAS CATO-C4X-1444107)
- 2-(tert-Butyl)acridin-9(10H)-one (CAS 103554-44-5)
- 8,11-Dimethoxy-13-(3-(trifluoromethyl)benzyl)-6,13-dihydro-5H-indolo[3,2-c]acridine (CAS 860787-16-2)
- (2R,5S)-1-(4-(2-(Benzyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl)-2-propylphenyl)-2,5-dimethylpiperazine (CAS 1669400-98-9)
- 5-Isopropyl-3,8-dimethylnaphthalen-2-ol (CAS 2102-75-2)
- 2-Ethyl-6-isopropylpyridine (CAS 74701-47-6)
- TAMRA-PEG2-Maleimide (CAS 2304558-24-3)
- (3-Amino-1-methyl-1H-pyrazol-5-yl)(1H-pyrazol-1-yl)methanone (CAS 1856018-75-1)
- Etomidate Impurity 65 (CAS 83763-26-2)
- Gambogin (CAS 173792-67-1)
- 3-Bromo-2-chloro-6-fluorotoluene (CAS 203302-92-5)
- methyl 3,4-dihydronaphthalene-2-carboxylate (CAS 51849-37-7)
- 4-(Methoxymethoxy)benzaldehyde (CAS 6515-21-5)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com