Upadacitinib Impurity 54 CAS 406-11-1

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.406-11-1
Molecular FormulaC5H6F6N2O
Molecular Weight224.10 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Upadacitinib Impurity 54 CAS 406-11-1 chemical structure

Description

The occurrence of Upadacitinib Impurity 54 is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Upadacitinib Impurity 54 (CAS 406-11-1) is a certified pharmaceutical impurity reference standard with the molecular formula C5H6F6N2O and a molecular weight of 224.10 g/mol.

Upadacitinib Impurity 54 (C5H6F6N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Upadacitinib Impurity 54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H6F6N2O
Molecular Weight224.10 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms2

Related Upadacitinib Standards

Recommended Standards

Why CATO?