5-((2-Fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione CAS 1035556-27-4
| CAS No. | 1035556-27-4 |
| Molecular Formula | C14H10FIN4O2 |
| Molecular Weight | 412.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-((2-Fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione (C14H10FIN4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 5-((2-Fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione (CAS 1035556-27-4), a certified reference material (molecular formula C14H10FIN4O2, MW 412.16 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-((2-Fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10FIN4O2 |
| Molecular Weight | 412.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 4 |
Related Fluoro Standards
- 5-Fluoro-1-((3aR,4R,6S,6aS)-6-(iodomethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione (CAS 61787-10-8)
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- 3-[1-(3-Fluoro-4-methylbenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775311-27-7)
- 1-(4-(3-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)propoxy)-3-hydroxyphenyl)ethanone (CAS 133454-57-6)
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Recommended Standards
- Tributylstannyl isonicotinate (CAS 5107-59-5)
- 2-(4-Bromophenyl)-N-(3-(trifluoromethyl)phenyl)-2H-tetrazole-5-carboxamide (CAS 1396799-47-5)
- 3-(2,4-Dibromo-6-fluorophenyl)-1,1-diisopropylthiourea (CAS 1980054-14-5)
- Guanosine-<SUP>15</SUP>N<SUB>5</SUB>-5′-monophosphate sodium salt (CAS 1257650-86-4)
- Torulene (CAS 547-23-9)
- Carfilzomib Impurity 26 (CAS 38155-18-9)
- 4-Benzylbenzyl acrylate (CAS 58419-97-9)
- 2-Bromo-3-chloro-1,4-difluorobenzene (CAS 1208077-34-2)
- 1-(Amino(phenyl)methyl)cyclopropanol (CAS 1391737-71-5)
- 2-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)ethan-1-amine (CAS 91337-46-1)
- Ethyl 2-(cyclopropylmethyl)-1,3-dithiane-2-carboxylate (CAS 527385-30-4)
- 5-(Piperidin-1-ylmethyl)isoxazole-3-carboxylic acid hydrobromide (CAS 1177299-39-6)
- (Z)-3-amino-2-(2-morpholinoacetyl)but-2-enenitrile (CAS 464891-08-5)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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