Betamethasone 17-Propionate-d5 CAS CATO-C4X-143735
| CAS No. | CATO-C4X-143735 |
| Molecular Formula | - |
| Molecular Weight | 453.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Betamethasone 17-Propionate-d5 (CAS CATO-C4X-143735), a certified reference material (molecular formula C25H28D5FO6, MW 453.56 g/mol) for analytical method development and quality control.
The molecular framework of Betamethasone 17-Propionate-d5 (C25H28D5FO6) is characterized by deuterium isotope labeling, a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H28D5FO6 |
| Molecular Weight | 453.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone impurity 106 (CAS 330157-03-4)
- Betamethasone Impurity 42 (CAS 25122-45-6)
- Betamethasone Impurity 111 (CAS CATO-C4X-1437111)
- Betamethasone Impurity 143 (CAS CATO-C4X-1437143)
- Betamethasone Impurity 28 (CAS CATO-C4X-143728)
- Betamethasone impurity 48 (CAS CATO-C4X-143748)
- Betamethasone Impurity 108 (CAS CATO-C4X-1437108)
- Betamethasone impurity 66 (CAS 4735-64-2)
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