3-(4-(Difluoromethoxy)phenyl)isoxazole-5-carboxylic acid CAS 1038311-61-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1038311-61-3
Molecular FormulaC11H7F2NO4
Molecular Weight255.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-(Difluoromethoxy)phenyl)isoxazole-5-carboxylic acid CAS 1038311-61-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 255.17 g/mol gives 3-(4-(Difluoromethoxy)phenyl)isoxazole-5-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(4-(Difluoromethoxy)phenyl)isoxazole-5-carboxylic acid (CAS 1038311-61-3) is a high-purity analytical reference standard with the molecular formula C11H7F2NO4 and a molecular weight of 255.17 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-(4-(Difluoromethoxy)phenyl)isoxazole-5-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 255.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(4-(Difluoromethoxy)phenyl)isoxazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H7F2NO4
Molecular Weight255.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms1

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