5-(Difluoromethoxy)-3-fluorobenzyl bromide CAS 1017779-39-3
| CAS No. | 1017779-39-3 |
| Molecular Formula | C8H6BrF3O |
| Molecular Weight | 255.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(Difluoromethoxy)-3-fluorobenzyl bromide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5-(Difluoromethoxy)-3-fluorobenzyl bromide (CAS 1017779-39-3), a certified reference material (molecular formula C8H6BrF3O, MW 255.03 g/mol) for analytical method development and quality control.
The molecular framework of 5-(Difluoromethoxy)-3-fluorobenzyl bromide (C8H6BrF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H6BrF3O |
| Molecular Weight | 255.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
Related Difluoromethoxy Standards
- 2-(Difluoromethoxy)-4-fluorobenzyl bromide (CAS 1017779-42-8)
- 4-(Difluoromethoxy)-3-Fluorobenzyl bromide (CAS 181806-49-5)
- n-(3-(Difluoromethoxy)phenyl)-2,2,2-trifluoroacetamide (CAS 647821-10-1)
- 3-(4-(Difluoromethoxy)phenyl)isoxazole-5-carboxylic acid (CAS 1038311-61-3)
- Ethyl 5-(difluoromethoxy)-1H-indole-3-carboxylate (CAS 1352397-09-1)
- 1-(3-(4-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)ethanamine (CAS 1707584-74-4)
- 1-(3-(2-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)ethanamine (CAS 1708250-74-1)
- 2-(3-(3-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)ethanamine (CAS 1779133-47-9)
Recommended Standards
- 2-(Bromomethyl)-4-(difluoromethoxy)-1-fluorobenzene (CAS 1017779-36-0)
- 1-(Bromomethyl)-4-(difluoromethoxy)-2-fluorobenzene (CAS 1017779-33-7)
- 1-Bromo-4-(2,2,2-trifluoroethoxy)benzene (CAS 106854-77-7)
- 5-Bromo-4-(difluoromethoxy)-6-methoxypyrimidine (CAS 2750605-72-0)
- tert-butyl N-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]carbamate (CAS 1357247-93-8)
- p-Terphenyl-d14 (CAS 1718-51-0)
- 1-(5-Bromo-7-methyl-1-benzofuran-2-yl)-2-methylpropan-1-one (CAS 1432681-76-9)
- (R)-2-(3,3-difluorocyclobutyl)propanoic acid (CAS 2248200-35-1)
- 1,4-Dichloro-2,5-bis(dichloromethyl)benzene (CAS 41999-84-2)
- N-((3,4-Dichlorobenzoyl)oxy)-2-(quinolin-8-yloxy)acetimidamide (CAS 88758-06-9)
- N-Hydroxy-2-(2-methyl-1-piperidinyl)-benzenecarboximidamide (CAS 1021244-04-1)
- 2-(2-Fluorobenzamido)benzoic acid (CAS 18600-60-7)
- Amiloride EP Impurity C (CAS 76599-74-1)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
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