Sacubitril Impurity 5 CAS 1038925-00-6
| CAS No. | 1038925-00-6 |
| Molecular Formula | C18H19NO |
| Molecular Weight | 265.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Sacubitril Impurity 5 (CAS 1038925-00-6, C18H19NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H19NO, Sacubitril Impurity 5 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 265.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Sacubitril Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19NO |
| Molecular Weight | 265.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 1 |
Related Sacubitril Standards
- Sacubitril Lactam (CAS 1038925-22-2)
- Sacubitril impurity 15 (CAS CATO-C4X-280915)
- Sacubitril impurity 41 (CAS 1038924-61-6)
- Sacubitril impurity 16 (CAS CATO-C4X-280916)
- Sacubitril impurity 9 (CAS CATO-C4X-28099)
- Sacubitril Impurity 57 (CAS 556828-95-6)
- Sacubitril Impurity 25 (CAS CATO-C4X-280925)
- Sacubitril Impurity 38 (CAS CATO-C4X-280938)
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