Sacubitril Impurity 25 CAS CATO-C4X-280925
| CAS No. | CATO-C4X-280925 |
| Molecular Formula | C19H21NO2 |
| Molecular Weight | 295.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Sacubitril Impurity 25 (CAS CATO-C4X-280925), a pharmacopoeial impurity reference standard (molecular formula C19H21NO2, MW 295.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Sacubitril Impurity 25 (C19H21NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21NO2 |
| Molecular Weight | 295.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Sacubitril Standards
- Sacubitril Impurity 57 (CAS 556828-95-6)
- Sacubitril impurity 9 (CAS CATO-C4X-28099)
- Sacubitril Impurity 38 (CAS CATO-C4X-280938)
- Sacubitril impurity 16 (CAS CATO-C4X-280916)
- Sacubitril impurity 11 (CAS 182192-86-5)
- Sacubitril Valsartan Sodium Impurity 3 (CAS 1907737-76-1)
- Sacubitril Lactam (CAS 1038925-22-2)
- Sacubitril Impurity 5 (CAS 1038925-00-6)
Recommended Standards
- Ergotamine Impurity 5 (CAS 4238-84-0)
- Nuciferine (CAS 475-83-2)
- Benzydamine impurity 6 (CAS 32852-16-7)
- N-Cyclohexyl-N’-[4-(2,3-epoxypropoxy)phenyl]urea-d5 (CAS 1329613-05-9)
- Alverine Impurity 20 Iodide (CAS 879718-23-7（free base）)
- Bilastine Impurity 45 (CAS CATO-C4X-225345)
- Pyridoxine impurity 4 (CAS 913696-26-1)
- 2-(5-Amino-2-methyl-1h-1,3-benzodiazol-1-yl)propan-1-ol (CAS 1343959-82-9)
- 7-Methoxy-N-(3-(trifluoromethyl)phenyl)quinoline-4-carboxamide (CAS 1624262-18-5)
- tert-Butyl 5-fluoro-2-nitrobenzoate (CAS 1192319-18-8)
- 2,3-Dichloropropionitrile (CAS 2601-89-0)
- Ivabradine impurity 77 (CAS CATO-C4X-111977)
- Indolin-5-ol (CAS 172078-33-0)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com