5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidine] dihydrochloride CAS 1047655-67-3
| CAS No. | 1047655-67-3 |
| Molecular Formula | C11H14N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidine] dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidine] dihydrochloride (CAS 1047655-67-3), molecular formula C11H14N2OHCl and molecular weight 226.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidine] dihydrochloride (C11H14N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H14N2O 2*HCl |
| Molecular Weight | 226.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related H Standards
- 1h-Spiro[furo[3,4-c]pyridine-3,4'-piperidine] dihydrochloride (CAS 1017599-04-0)
- SPIRO[IMIDAZOLIDINE-4,1'-INDENE]-2,5-DIONE (CAS 102325-53-1)
- Spiro[adamantane-2,3'-indole]-2'-amine hydrochloride (CAS 1029986-95-5)
- 1'H-Spiro[piperidine-4,4'-quinolin]-2'(3'H)-one hydrochloride (CAS 1032143-27-3)
- spiro[7H-furo[3,4-b]pyridine-5,4'-piperidine] (CAS 1036408-86-2)
- Spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one hydrochloride (CAS 1038866-43-1)
- Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride (CAS 1038866-44-2)
- Spiro[cyclopentane-1,1'-indene] (CAS 10408-80-7)
Recommended Standards
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- Clotrimazole Impurity 20 (CAS 27023-37-6)
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- (Methoxycarbonyl)-D-leucine (CAS 791635-26-2)
- 1-Benzyl-7-fluoro-3-(4-bromophenyl)-1H-indazole (CAS 1809161-44-1)
- 5,7-Dichloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine (CAS 1601808-18-7)
- 5-(Phenylthio)pentan-1-amine (CAS 642092-78-2)
- Peptide WE-14 (CAS 115136-18-0)
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