Clotrimazole Impurity 20 CAS 27023-37-6
| CAS No. | 27023-37-6 |
| Molecular Formula | C19H14Cl2 |
| Molecular Weight | 313.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Clotrimazole Impurity 20.
CATO supplies Clotrimazole Impurity 20 (CAS 27023-37-6), a pharmacopoeial impurity reference standard (molecular formula C19H14Cl2, MW 313.22 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H14Cl2, Clotrimazole Impurity 20 contains chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 313.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Clotrimazole Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14Cl2 |
| Molecular Weight | 313.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
Related Clotrimazole Standards
- Clotrimazole Impurity 22 (CAS 59154-29-9)
- Clotrimazole EP Impurity C (CAS 42074-68-0)
- Clotrimazole EP Impurity F (CAS 15469-97-3)
- Clotrimazole Impurity 17 (CAS 717109-42-7)
- Clotrimazole Impurity 8 (CAS CATO-C4X-15698)
- Clotrimazole Impurity 18 (CAS 717109-43-8)
- Clotrimazole Impurity 9 (CAS 23593-68-2)
- Clotrimazole Impurity 29 (CAS 103855-36-3)
Recommended Standards
- Bifonazole Impurity 15 (CAS CATO-C4X-156015)
- rel-(1R,3S)-Ethyl 3-((Z)-2-chloro-2-(4-chlorophenyl)vinyl)-2,2-dimethylcyclopropanecarboxylate (CAS 78479-01-3)
- 4-Nitro-2-(4-nitrophenyl)isoindoline-1,3-dione (CAS 53555-13-8)
- Losartan Impurity 47 (CAS CATO-C4X-168347)
- Cefpirome Impurity 31 (CAS CATO-C4X-120731)
- Azlocillin Impurity 9 (CAS CATO-C4X-23209)
- Darolutamide Impurity 41 (CAS CATO-C4X-310641)
- 1-(5-Bromo-2,3-difluorophenyl)piperidin-4-ol (CAS 1704067-19-5)
- 6-Fluoro-3-isobutyl-1h-indole (CAS 1002332-01-5)
- 5-Hydroxy-4-(4-(trifluoromethyl)phenyl)isoquinolin-1(2H)-one (CAS 656234-33-2)
- 3,9-bis(2-chloroethoxy)-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-bis(2-chloroethyloxy)-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 6262-87-9 A833898 (CAS 6262-87-9)
- 2,2’-Dimethyl-3,3’-bipyridine (CAS 86156-55-0)
- 5-Bromo-1H-1,2,4-triazole-3-carboxylic acid (CAS 674287-63-9)
- KALA Amphipathic Peptide (CAS 187987-64-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com