2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)acetic acid CAS 1048963-34-3
| CAS No. | 1048963-34-3 |
| Molecular Formula | C7H10F2O3 |
| Molecular Weight | 180.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)acetic acid (CAS 1048963-34-3), a certified reference material (molecular formula C7H10F2O3, MW 180.15 g/mol) for analytical method development and quality control.
2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)acetic acid (C7H10F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10F2O3 |
| Molecular Weight | 180.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 4,4-Difluoro-1-hydroxycyclohexane-1-carboxylic acid (CAS 1075221-15-6)
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- 1,1-Difluoro-4-phenylbut-3-yn-2-one (CAS 117710-72-2)
- 2,2-difluoro-2-(pyrazin-2-yl)acetic acid (CAS 1342462-39-8)
- Ethyl 3,3-difluoro-2-hydroxypent-4-enoate (CAS 1365970-40-6)
- (R)-5,5-difluoro-2-methyltetrahydro-2H-pyran-2-carboxylic acid (CAS 1447941-12-9)
- 5,5-Difluoro-2-methyltetrahydro-2H-pyran-2-carboxylic acid (CAS 1447942-76-8)
- (S)-5,5-difluoro-2-methyltetrahydro-2H-pyran-2-carboxylic acid (CAS 1447942-80-4)
Recommended Standards
- NSC 61610, >98% (CAS 27111-43-9)
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- 5,7-Difluoroquinolin-4-amine (CAS 1065092-27-4)
- (2E)-2-[(Pyridin-3-yl)methylidene]-2,3,4,9-tetrahydro-1H-carbazol-1-one (CAS 866138-46-7)
- 4-Cyanobicyclo[2.2.1]Heptane-1-carboxylic acid (CAS 15448-86-9)
- (8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)methanol (CAS 1209122-81-5)
- 2-Amino-1-(2-fluorophenyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 344301-95-7)
- 3-Phenyl-1-(p-tolyl)-1,4-dihydrochromeno[4,3-b]pyrrole (CAS 654651-10-2)
- 4-Tosylcinnoline (CAS 62196-38-7)
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- Betahistine Impurity 24 (CAS CATO-C4X-183824)
- 5-Bromo-1-cyclopropyl-1H-pyrrolo[2,3-b]pyridine-2,3-dione (CAS 1956379-40-0)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
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