(2S,4R)-4-(3,4-dichlorobenzyl)pyrrolidine-2-carboxylic acid CAS 1049981-41-0
| CAS No. | 1049981-41-0 |
| Molecular Formula | C12H13Cl2NO2 |
| Molecular Weight | 274.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2S,4R)-4-(3,4-dichlorobenzyl)pyrrolidine-2-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2S,4R)-4-(3,4-dichlorobenzyl)pyrrolidine-2-carboxylic acid (CAS 1049981-41-0) is a high-purity analytical reference standard with the molecular formula C12H13Cl2NO2 and a molecular weight of 274.14 g/mol.
(2S,4R)-4-(3,4-dichlorobenzyl)pyrrolidine-2-carboxylic acid (C12H13Cl2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2S,4R)-4-(3,4-dichlorobenzyl)pyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13Cl2NO2 |
| Molecular Weight | 274.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2S,4R)-4-(2,4-dichlorobenzyl)pyrrolidine-2-carboxylic acid (CAS 1049980-61-1)
- 2,4-Dichloro-3-phenylquinoline (CAS 108832-15-1)
- 2,6-Dichloro-4-phenylquinoline (CAS 10352-30-4)
- 1-(tert-Butyl)-3-iodo-5-methylbenzene (CAS 111220-30-5)
- 1-(3,4-Dimethoxybenzyl)piperidine-2,4-dione (CAS 99539-45-4)
- (S)-Methyl 2-((methoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetate (CAS 1009120-03-9)
- 3-Methyl-2-phenylbutan-2-ol (CAS 4383-11-3)
- (2E)-1-(2,4-Dimethoxyphenyl)-3-(2-ethoxyphenyl)prop-2-en-1-one (CAS 865273-62-7)
- (R)-1,2,3,4-Tetrahydronaphthalene-2-carboxylic acid (CAS 38157-15-2)
- (6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol (CAS 280752-78-5)
- N-(2-(Dimethylamino)-4,6-dimethylpyrimidin-5-yl)furan-2-carboxamide (CAS 1448052-57-0)
- Boceprevir Impurity 21 (CAS 1568066-82-9)
- Aztreonam impurity 61 (CAS CATO-C4X-152261)
- Semaglutide impurity 57 (CAS 2773558-06-6)
Why CATO?
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