Vildagliptin Impurity 64 CAS 105-48-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.105-48-6
Molecular FormulaC5H9ClO2
Molecular Weight136.58 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Vildagliptin Impurity 64 CAS 105-48-6 chemical structure

Description

CATO supplies Vildagliptin Impurity 64 (CAS 105-48-6), a pharmacopoeial impurity reference standard (molecular formula C5H9ClO2, MW 136.58 g/mol) used for the identification and quantification of trace impurities in APIs.

Vildagliptin Impurity 64 (C5H9ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Vildagliptin Impurity 64 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H9ClO2
Molecular Weight136.58 g/mol
Purity>95%
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityContains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1957
Halogen ContentCl-containing

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