Promethazine Impurity 71 CAS CATO-C4X-141871

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-141871
Molecular FormulaC4H9ClN2O
Molecular Weight136.58 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Promethazine Impurity 71 CAS CATO-C4X-141871 chemical structure

Description

CATO supplies Promethazine Impurity 71 (CAS CATO-C4X-141871), a pharmacopoeial impurity reference standard (molecular formula C4H9ClN2O, MW 136.58 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Promethazine Impurity 71 is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 136.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC4H9ClN2O
Molecular Weight136.58 g/mol
Purity≥95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
Halogen ContentCl-containing
Nitrogen Atoms2

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