N-[(1R,2R)-2-Aminocyclohexyl]-N'-[(8α,9S)-6'-methoxycinchonan-9-yl]thiourea CAS 1052184-48-1

Description

The molecular framework of N-[(1R,2R)-2-Aminocyclohexyl]-N'-[(8α,9S)-6'-methoxycinchonan-9-yl]thiourea (C27H37N5OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

N-[(1R,2R)-2-Aminocyclohexyl]-N'-[(8α,9S)-6'-methoxycinchonan-9-yl]thiourea (CAS 1052184-48-1), molecular formula C27H37N5OS and molecular weight 479.68 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-[(1R,2R)-2-Aminocyclohexyl]-N'-[(8α,9S)-6'-methoxycinchonan-9-yl]thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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