Atomoxetine Impurity 33 CAS CATO-C4X-155033
| CAS No. | CATO-C4X-155033 |
| Molecular Formula | C33H37NO2 |
| Molecular Weight | 479.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Atomoxetine Impurity 33 (CAS CATO-C4X-155033) is a certified pharmaceutical impurity reference standard with the molecular formula C33H37NO2 and a molecular weight of 479.65 g/mol.
Atomoxetine Impurity 33 (C33H37NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C33H37NO2 |
| Molecular Weight | 479.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Atomoxetine Standards
- Atomoxetine Impurity 46 (CAS CATO-C4X-155046)
- Atomoxetine Impurity 54 (CAS CATO-C4X-155054)
- Atomoxetine Impurity 3 (CAS 93982-97-9)
- Atomoxetine Impurity 18 (CAS CATO-C4X-155018)
- Atomoxetine Impurity 21 (CAS CATO-C4X-155021)
- Atomoxetine Impurity 23 (CAS CATO-C4X-155023)
- Atomoxetine Impurity 22 (CAS 881995-45-5)
- Atomoxetine Impurity 26 (CAS CATO-C4X-155026)
Recommended Standards
- Pingpeimine B (CAS 82851-52-3)
- N-(4-chloro-2-(trifluoromethyl)phenyl)-1-(2,4-dichloro-5-methoxyphenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 339015-17-7)
- O-Demethoxypropane Aliskiren (CAS 949925-77-3)
- N-[(1R,2R)-2-Aminocyclohexyl]-N'-[(8α,9S)-6'-methoxycinchonan-9-yl]thiourea (CAS 1052184-48-1)
- Niraparib Impurity 8 (CAS 1289174-44-2)
- Perphenazine EP Impurity B (CAS 3533-97-9)
- Calcium Dobesilate Impurity N3 (CAS 17724-11-7)
- 4-Chloro-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 68755-29-3)
- (S)-Benzyl (2-oxopyrrolidin-3-yl)carbamate (CAS 118507-50-9)
- Ethyl 4-acetyl-5-methylisoxazole-3-carboxylate (CAS 15911-11-2)
- Colesevelam Hydrochloride (CAS 182815-44-7)
- 2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine (CAS 1030420-77-9)
- 3-Oxoisoindoline-1-carboxamide (CAS 22858-91-9)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
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