Paclitaxel Impurity 57 CAS 1053697-17-8
| CAS No. | 1053697-17-8 |
| Molecular Formula | C47H50N2O15 |
| Molecular Weight | 882.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 882.90 g/mol gives Paclitaxel Impurity 57 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Paclitaxel Impurity 57 (CAS 1053697-17-8) is a certified pharmaceutical impurity reference standard with the molecular formula C47H50N2O15 and a molecular weight of 882.90 g/mol.
Structurally, Paclitaxel Impurity 57 (C47H50N2O15) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 24.0, corresponding to approximately 24 ring(s) or double-bond equivalent(s). With a molecular weight of 882.90 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C47H50N2O15 |
| Molecular Weight | 882.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Paclitaxel Standards
- Paclitaxel EP Impurity O (CAS 219783-77-4)
- Paclitaxel EP Impurity M (CAS 932042-85-8)
- Paclitaxel EP Impurity J (CAS 2757197-26-3)
- Paclitaxel EP Impurity L (CAS 92950-39-5)
- Paclitaxel EP Impurity P (CAS 173101-56-9)
- Paclitaxel EP Impurity F (CAS 153083-53-5)
- Paclitaxel 13C [~1.0Mg/Ml](P) (In Solution) (CAS 379688-61-6)
- Paclitaxel-d5 (CAS 1129540-33-5)
Recommended Standards
- N,N',N''-((((2R,3S,6R,7S,10R,11S)-2,6,10-Trimethyl-4,8,12-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl)tris(azanediyl))tris(2-oxoethane-2,1-diyl))tris(2,3-dihydroxybenzamide) (CAS 95536-41-7)
- 6,6',6'',6'''-(Pyrene-1,3,6,8-tetrayl)tetrakis(2-naphthoicacid) (CAS 2010983-66-9)
- Tedizolid Impurity 10 (CAS 1220910-90-6)
- 1,8,15,22-Tetraphenoxy-29H,31H-phthalocyanine (CAS 77474-60-3)
- Fasudil Impurity 6 (CAS 2044706-58-1)
- Valaciclovir EP Impurity E (CAS 124832-31-1)
- Pemafibrate Impurity 54 (CAS CATO-C4X-290354)
- 1-(1-Boc-3-azetidinyl)pyrazole-4-boronic Acid Pinacol Ester (CAS 877399-35-4)
- 3-(4-Bromo-3,5-dimethyl-1h-pyrazol-1-yl)propan-1-amine (CAS 1000802-72-1)
- Methyl 2-(3,4,4-trifluorobut-3-ene-1-sulfonyl)acetate (CAS 339020-20-1)
- 2,4,6-Tris(cyclohexyloxy)-1,3,5,2,4,6-trioxatriborinane (CAS 1172-69-6)
- Piracetam Impurity 17 (CAS 64026-51-3)
- 6-Chloro-N-(3-methoxypropyl)pyrazin-2-amine (CAS 941294-49-1)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com