Emtricitabine impurity 61 CAS 1055312-45-2
| CAS No. | 1055312-45-2 |
| Molecular Formula | C8H9FN2O3S |
| Molecular Weight | 232.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Emtricitabine impurity 61 (C8H9FN2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 232.23 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Emtricitabine impurity 61 (CAS 1055312-45-2), a pharmacopoeial impurity reference standard (molecular formula C8H9FN2O3S, MW 232.23 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9FN2O3S |
| Molecular Weight | 232.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Emtricitabine Standards
- Emtricitabine Impurity 4 (CAS 145397-25-7)
- Emtricitabine impurity 49 (CAS CATO-C4X-123249)
- Emtricitabine impurity 54 (CAS 145397-26-8)
- Emtricitabine Impurity 22 (CAS CATO-C4X-123222)
- Emtricitabine Impurity 35 (CAS 1238210-14-4)
- Emtricitabine Impurity 23 (CAS CATO-C4X-123223)
- Emtricitabine Impurity 24 (CAS CATO-C4X-123224)
- Emtricitabine Impurity 28 (CAS CATO-C4X-123228)
Recommended Standards
- Tadalafil Impurity 164 (CAS 58979-02-5)
- Diflunisal impurity 5 (CAS 53591-79-0)
- Triethyl Methanetricarboxylate (CAS 6279-86-3)
- Clemastine Impurity 27 (CAS 10095-17-7)
- Perphenazine DiHCl (Fluphenazine Dihydrochloride EP Impurity E DiHCl) (CAS 2015-28-3)
- Rifaximin Impurity B (CAS 1351775-03-5)
- Finerenone impurity 179 (CAS CATO-C4X-2880179)
- (S)-1'-(tert-Butyl)-5,7-dihydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one (CAS 2408280-91-9)
- 4-(Benzylamino)-5-bromopyridine-3-sulfonamide (CAS 1352540-96-5)
- (1-ethyl-1H-1,2,3-triazol-5-yl)methanol (CAS 77177-13-0)
- N-methyl-1-(o-tolyl)methanamine hydrochloride (CAS 1071580-83-0)
- 2-Ethoxy-6-methoxyquinoline (CAS 72543-50-1)
- 8-Bromo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1391002-24-6)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com