Perphenazine DiHCl (Fluphenazine Dihydrochloride EP Impurity E DiHCl) CAS 2015-28-3
| CAS No. | 2015-28-3 |
| Molecular Formula | C21H26ClN3OS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Perphenazine DiHCl (Fluphenazine Dihydrochloride EP Impurity E DiHCl) (CAS 2015-28-3) is a certified pharmaceutical impurity reference standard with the molecular formula C21H26ClN3OSHCl and a molecular weight of 440.43 g/mol.
Based on its molecular formula C21H26ClN3OSHCl, Perphenazine DiHCl (Fluphenazine Dihydrochloride EP Impurity E DiHCl) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 440.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H26ClN3OS 2*HCl |
| Molecular Weight | 440.43 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Perphenazine Standards
- Perphenazine EP Impurity A (CAS 10078-25-8)
- Perphenazine-D8 (as Dihydrochloride) (CAS 1189961-11-2)
- Perphenazine Impurity 6 (CAS 1254074-25-3)
- Perphenazine-d4 (CAS 155593-75-2)
- Perphenazine-D8 dihydrochloride (CAS 2070015-23-3)
- Perphenazine Impurity 5 (CAS 2760728-14-9)
- Perphenazine Impurity C27 (CAS 2765-59-5)
- Perphenazine EP Impurity B (CAS 3533-97-9)
Recommended Standards
- Regorafenib Impurity 79 (CAS CATO-C4X-104779)
- Avanafil Impurity 52 (CAS CATO-C4X-111852)
- Baclofen Impurity 68 (CAS CATO-C4X-101268)
- (E)-5-aminopent-2-enoic acid (CAS 102845-70-5)
- 4-Carbazol-9-yl-3-hydroxy-butyric acid (CAS 1171934-73-8)
- Niraparib Impurity 36 (CAS 1140736-91-9)
- 2-Benzylpyrrolidine-2-carboxylic acid (CAS 72518-40-2)
- 5-Oxopyrrolidine-2-carboxamide (CAS 5626-52-8)
- 4-Carboethoxy-3-thiomorpholinomethyl benzophenone (CAS 898762-94-2)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
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