S-(-)-Felodipine CAS 105618-03-9
| CAS No. | 105618-03-9 |
| Molecular Formula | C18H19Cl2NO4 |
| Molecular Weight | 384.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), S-(-)-Felodipine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies S-(-)-Felodipine (CAS 105618-03-9), a certified reference material (molecular formula C18H19Cl2NO4, MW 384.25 g/mol) for analytical method development and quality control.
S-(-)-Felodipine (C18H19Cl2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H19Cl2NO4 |
| Molecular Weight | 384.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- R-(+)-Felodipine (CAS 119945-59-4)
- Felodipine Impurity 28 (CAS CATO-C4X-109428)
- Felodipine Impurity 29 (CAS CATO-C4X-109429)
- Felodipine Impurity 30 (CAS CATO-C4X-109430)
- Felodipine Impurity 31 (CAS CATO-C4X-109431)
- Felodipine (CAS 72509-76-3)
- Felodipine EP Impurity A (CAS 96382-71-7)
- rac Felodipine-d3 (CAS 1189970-31-7)
Recommended Standards
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- Bortezomib Impurity 7 (CAS 1132709-15-9)
- Bortezomib Impurity 6 (CAS 1132709-14-8)
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- Methyl({[1-(propan-2-yl)-1h-pyrazol-5-yl]methyl})amine (CAS 1007464-33-6)
- 3-(2-Hydroxypyrimidin-5-yl)benzaldehyde (CAS 1111104-14-3)
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- 4-(1,2,3-Thiadiazol-4-yl)phenyl N-(2-methylphenyl)carbamate (CAS 337924-61-5)
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- Cabe Palace Suya Inkstone I TFA (CAS CATO-C4X-191122)
- ([D?]Val?·1?)-C-Peptide (human) (CAS 1802078-41-6)
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