Felodipine Impurity 28 CAS CATO-C4X-109428
| CAS No. | CATO-C4X-109428 |
| Molecular Formula | C18H19Cl2NO4 |
| Molecular Weight | 384.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Felodipine Impurity 28 (CAS CATO-C4X-109428) is a certified pharmaceutical impurity reference standard with the molecular formula C18H19Cl2NO4 and a molecular weight of 384.25 g/mol.
Felodipine Impurity 28 (C18H19Cl2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19Cl2NO4 |
| Molecular Weight | 384.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Felodipine Standards
- S-(-)-Felodipine (CAS 105618-03-9)
- R-(+)-Felodipine (CAS 119945-59-4)
- Felodipine Impurity 29 (CAS CATO-C4X-109429)
- Felodipine Impurity 30 (CAS CATO-C4X-109430)
- Felodipine Impurity 31 (CAS CATO-C4X-109431)
- Felodipine (CAS 72509-76-3)
- Felodipine EP Impurity A (CAS 96382-71-7)
- rac Felodipine-d3 (CAS 1189970-31-7)
Recommended Standards
- 2-(2,4-Dichlorophenoxy)-N-(3,4-dimethoxyphenethyl)acetamide (CAS 133611-82-2)
- 9,10-Dioxo-9,10-dihydroanthracene-1,4,5,8-tetracarboxylicacid (CAS 109039-74-9)
- Amlodipine Impurity 52 (CAS CATO-C4X-109552)
- 2-(5-Bromo-2-(tosylimino)pyridin-1(2H)-yl)acetamide (CAS 1005785-49-8)
- Cinacalcet Impurity 17 (CAS 49681-33-6)
- Glycerol Impurity 45 (CAS CATO-C4X-217145)
- Thioridazine Impurity 1 (CAS 7643-08-5)
- 2-(2-Bromo-5-cyano-4-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805432-35-2)
- Methyl (2,5-dioxo-2,5-dihydro-1H-imidazol-4-yl)carbamate (CAS 188558-84-1)
- 3-(2,4-Dichloro-5-fluorophenyl)-1-(2-methoxyphenyl)-1H-pyrazole-5-carboxylic acid (CAS 618383-00-9)
- N-(5-((2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)pentanamide (CAS 392296-11-6)
- 1-(3,3,3-trifluoropropyl)-1H-pyrazol-5-amine (CAS 1245772-93-3)
- 3-Nitro-5-(pyridin-3-yloxy)aniline (CAS 208122-66-1)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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