Felodipine CAS 72509-76-3
| CAS No. | 72509-76-3 |
| Molecular Formula | C18H19Cl2NO4 |
| Molecular Weight | 384.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Felodipine.
CATO supplies Felodipine (CAS 72509-76-3), a certified reference material (molecular formula C18H19Cl2NO4, MW 384.25 g/mol) for analytical method development and quality control.
Structurally, Felodipine (C18H19Cl2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 384.25 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19Cl2NO4 |
| Molecular Weight | 384.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Felodipine Standards
- S-(-)-Felodipine (CAS 105618-03-9)
- R-(+)-Felodipine (CAS 119945-59-4)
- Felodipine Impurity 28 (CAS CATO-C4X-109428)
- Felodipine Impurity 29 (CAS CATO-C4X-109429)
- Felodipine Impurity 30 (CAS CATO-C4X-109430)
- Felodipine Impurity 31 (CAS CATO-C4X-109431)
- Felodipine EP Impurity A (CAS 96382-71-7)
- rac Felodipine-d3 (CAS 1189970-31-7)
Recommended Standards
- Amlodipine Impurity 52 (CAS CATO-C4X-109552)
- Amlodipine Impurity N5 (CAS 107812-86-2)
- 8-(2,4-Dichlorobenzoyl)-3-propyl-1,3,8-triazaspiro[4.5]decane-2,4-dione (CAS 1021210-54-7)
- 4-(4-Bromophenyl)-1-tert-butoxycarbonyl-piperidine-4-carboxylic acid (CAS 1076197-05-1)
- 2-(Methylthio)-N-(2-phenoxyphenyl)benzamide (CAS 838887-18-6)
- 1,2-Diamino-4,5-dichlorobenzene (CAS 5348-42-5)
- (6-Methyl-3-(methylthio)-5-oxo-1,2,4-triazin-4(5H)-yl)methyl 2-(2-methoxyphenoxy)acetate (CAS 877648-47-0)
- (E)-Metominostrobin (CAS 133408-50-1)
- 1-Boc-5-fluoro-1H-indole (CAS 129822-47-5)
- Dodecyl dihydrogen borate (CAS 134638-14-5)
- 1-Ethyl-2-(7-(1-ethyl-3,3-dimethylindolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-3H-indol-1-ium iodide (CAS 17094-17-6)
- 4-(2-Bromobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326814-87-2)
- 3-Fluoro-4-((tetrahydro-2H-pyran-4-yl)oxy)aniline (CAS 1054316-88-9)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com