Nilotinib Impurity 25 CAS 41574-91-8
| CAS No. | 41574-91-8 |
| Molecular Formula | C9H12N2O2 |
| Molecular Weight | 180.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nilotinib Impurity 25.
CATO supplies Nilotinib Impurity 25 (CAS 41574-91-8), a pharmacopoeial impurity reference standard (molecular formula C9H12N2O2, MW 180.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Nilotinib Impurity 25 (C9H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nilotinib Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H12N2O2 |
| Molecular Weight | 180.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 2 |
Related Nilotinib Standards
- (Z)-Nilotinib Impurity 37 (CAS 75415-01-9)
- Nilotinib 2-Pyridinyl Impurity (CAS 66521-65-1)
- Nilotinib Impurity 50 (CAS CATO-C4X-125650)
- Nilotinib Impurity 51 (CAS CATO-C4X-125651)
- Nilotinib Impurity 40 (CAS 859026-97-4)
- Nilotinib Impurity 17 (CAS 18595-17-0)
- Nilotinib EP Impurity B (CAS 18595-18-1)
- Nilotinib Hydrochloride Monohydrate EP Impurity C (CAS 2458-12-0)
Recommended Standards
- Bisoprolol Impurity 37 (CAS 4204-78-8)
- Prazosin EP Impurity D (CAS 40172-95-0)
- (2R,3S)-3-amino-2-hydroxy-3-phenylpropanamide (CAS CATO-C4X-111546)
- N-Nitroso Rivastigmine Impurity 30 (CAS CATO-C4X-138430)
- Amylmetacresol EP Impurity E (CAS 173851-66-6)
- Flurbiprofen Impurity 84 (CAS 5001-96-7)
- Pazufloxacin Impurity 8 (CAS 136905-87-8)
- 4-Iodo-3-methylpyridine (CAS 22282-64-0)
- 7-Chloro-3-methylquinazoline-2,4(1H,3H)-dione (CAS 93355-81-8)
- 2-(3,4-Dimethoxyphenyl)ethane-1-sulfonyl chloride (CAS 1017226-42-4)
- (2R,3R,4R,5R)-5-(benzyloxymethyl)-3-[tert-butyl(diphenyl)silyl]oxy-tetrahydrofuran-2,4-diol (CAS 1583259-73-7)
- Landiolol Impurity 128 (CAS CATO-C4X-2621128)
- 3-Amino-2-(methylamino)benzonitrile (CAS 1263413-45-1)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com