Butylphthalide Impurity 68 CAS 105694-44-8
| CAS No. | 105694-44-8 |
| Molecular Formula | C8H5BrO2 |
| Molecular Weight | 213.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Butylphthalide Impurity 68 (CAS 105694-44-8), a pharmacopoeial impurity reference standard (molecular formula C8H5BrO2, MW 213.03 g/mol) used for the identification and quantification of trace impurities in APIs.
Butylphthalide Impurity 68 (C8H5BrO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Butylphthalide Impurity 68 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrO2 |
| Molecular Weight | 213.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
Related Butylphthalide Standards
- Butylphthalide Impurity 67 (CAS 102308-43-0)
- Butylphthalide Impurity 31 (CAS 96610-56-9)
- Butylphthalide Impurity 51 (CAS 17689-42-8)
- Butylphthalide Impurity 47 (CAS 380905-48-6)
- Butylphthalide Impurity N4 (CAS 168288-19-5)
- Butylphthalide Impurity 21 (CAS 152567-80-1)
- Butylphthalide Impurity 3 (CAS 550-37-8)
- Butylphthalide Impurity 38 (CAS 162050-43-3)
Recommended Standards
- Remdesivir Impurity 12 (CAS 937046-98-5)
- 3-Bromophthalide (CAS 6940-49-4)
- 2-Butyl-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione (CAS 1104637-43-5)
- 6-Bromoisobenzofuran-1(3H)-one (CAS 19477-73-7)
- Formoterol EP Impurity C (CAS 1795135-61-3)
- Orforglipron impurity 75 (CAS CATO-C4X-323475)
- Avatrombopag Impurity 69 (CAS 91695-59-9)
- 3-Chloro-N-(2,4-dibromophenyl)-2,2-dimethylpropanamide (CAS 454473-75-7)
- 4-Bromo-2-(difluoromethyl)-6-(trifluoromethyl)pyridin-3-ol (CAS 1805170-55-1)
- 4-Pyridin-4-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta-[c]quinoline-8-carboxylic acid 4190AE 485320-01-2 C18H16N2O2 (CAS 485320-01-2)
- Cyclohexyl(3-fluoro-4-methoxyphenyl)methanone (CAS 943111-02-2)
- 3-(Benzyloxy)-4-chloroaniline (CAS 76464-57-8)
- Bis(glycylglycinato)nickel (CAS 16884-48-3)
- Semaglutide238 (CAS CATO-C4X-2226238)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com