Butylphthalide Impurity 3 CAS 550-37-8
| CAS No. | 550-37-8 |
| Molecular Formula | C12H14O3 |
| Molecular Weight | 206.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Butylphthalide Impurity 3 (CAS 550-37-8, C12H14O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Butylphthalide Impurity 3 (C12H14O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Butylphthalide Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14O3 |
| Molecular Weight | 206.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Butylphthalide Standards
- Butylphthalide Impurity N4 (CAS 168288-19-5)
- Butylphthalide Impurity 21 (CAS 152567-80-1)
- Butylphthalide Impurity 38 (CAS 162050-43-3)
- Butylphthalide Impurity 52 (CAS 74459-23-7)
- Butylphthalide Impurity 6 (CAS 162050-42-2)
- Butylphthalide Impurity 24 (CAS 20871-32-3)
- Butylphthalide Impurity 11 (CAS 111943-62-5)
- Butylphthalide Impurity 47 (CAS 380905-48-6)
Recommended Standards
- Pemetrexed Impurity 75 (CAS 240407-05-0)
- Pemetrexed Impurity 42 (CAS 912935-56-9)
- Pemetrexed Impurity (CAS CATO-C4X-172640)
- Ozagrel Impurity 12 (CAS 530145-11-0)
- Promethazine Impurity 46 (CAS CATO-C4X-141846)
- Atogepant Impurity 36 (CAS CATO-C4X-328536)
- Phenacetin Impurity 1 (CAS 3154-18-5)
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- Methyl 3-[(quinoxalin-2-ylsulfanyl)methyl]benzoate (CAS 285986-74-5)
- n-Cyclopropyl-3-(o-tolyl)cyclobutan-1-amine hydrochloride (CAS 1354954-29-2)
- 2,4,6-Trimethoxybenzyl bromide (CAS 1094663-93-0)
- Cefcapene Impurity 60 (CAS CATO-C4X-182460)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com