Ambroxol impurity 68 CAS 105735-86-2

Description

Compared with other compounds in its class, the molecular weight of 392.09 g/mol gives Ambroxol impurity 68 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ambroxol impurity 68 (CAS 105735-86-2) is a certified pharmaceutical impurity reference standard with the molecular formula C13H16Br2N2O2 and a molecular weight of 392.09 g/mol.

Ambroxol impurity 68 (C13H16Br2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ambroxol impurity 68 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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