Ambroxol Hydrochloride EP Impurity B CAS CATO-C4X-108546
| CAS No. | CATO-C4X-108546 |
| Molecular Formula | C14H18Br2N2O |
| Molecular Weight | 390.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ambroxol Hydrochloride EP Impurity B (CAS CATO-C4X-108546) is a certified pharmaceutical impurity reference standard with the molecular formula C14H18Br2N2O and a molecular weight of 390.11 g/mol.
The molecular framework of Ambroxol Hydrochloride EP Impurity B (C14H18Br2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ambroxol Hydrochloride EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18Br2N2O |
| Molecular Weight | 390.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Ambroxol Standards
- Ambroxol Impurity 17 (CAS CATO-C4X-108517)
- Ambroxol EP Impurity B (CAS 18683-95-9)
- Ambroxol impurity 99 (CAS CATO-C4X-108599)
- Ambroxol impurity 64 (CAS CATO-C4X-108564)
- Ambroxol impurity 106 (CAS CATO-C4X-1085106)
- Ambroxol Impurity 104 (CAS CATO-C4X-1085104)
- Ambroxol impurity 113 (CAS 131417-90-8)
- Ambroxol Impurity 48 (CAS 2646700-91-4)
Recommended Standards
- 1,1,1,7,7,7-Hexafluoro-2,6-dihydroxy-2,6-bis(trifluoromethyl)heptan-4-one (CAS 10487-11-3)
- Bromhexine Impurity 46 (CAS 3472-84-2)
- 3-((4-Bromophenyl)thio)-1-(3,4-dichlorophenyl)propan-1-one (CAS 882748-43-8)
- Bromhexine Impurity 20 (CAS CATO-C4X-106020)
- LCZ-696 Impurity 4 (CAS 1038924-97-8)
- Vericiguat Impurity 90 (CAS CATO-C4X-289690)
- Ciprofloxacin impurity 45 (CAS 93106-58-2)
- tert-butyl N-(7-fluoro-3-hydroxy-1,5-naphthyridin-2-yl)carbamate (CAS 2435612-65-8)
- (4-Bromo-2-fluoro-[1,1'-biphenyl]-3-yl)(methyl)sulfane (CAS 2624417-44-1)
- 1-((1-(4-Fluorophenyl)-1h-tetrazol-5-yl)methyl)piperazine dihydrochloride (CAS 1351614-10-2)
- {[(4-tert-Butylphenyl)methyl]sulfanyl}methanimidamide hydrobromide (CAS 125988-33-2)
- 3-[(2,3-dihydro-benzo[1,4]dioxine-6-carbonyl)-amino]-propionic acid 335212-81-2 (CAS 335212-81-2)
- 5-(2-Aminothiazol-4-yl)pyrimidine-2,4(1H,3H)-dione (CAS 7597-80-0)
- Gastric Inhibitory Polypeptide (6-30) amide (human) (CAS 1139691-72-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com