7-Chloro-2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-3-[(tetrahydro-2-furanyl)methyl]-4(3H)-quinazolinone CAS 1057725-14-0
| CAS No. | 1057725-14-0 |
| Molecular Formula | C21H19ClN2O5S |
| Molecular Weight | 446.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Chloro-2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-3-[(tetrahydro-2-furanyl)methyl]-4(3H)-quinazolinone is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-Chloro-2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-3-[(tetrahydro-2-furanyl)methyl]-4(3H)-quinazolinone (CAS 1057725-14-0) is a high-purity analytical reference standard with the molecular formula C21H19ClN2O5S and a molecular weight of 446.90 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 7-Chloro-2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-3-[(tetrahydro-2-furanyl)methyl]-4(3H)-quinazolinone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 446.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 7-Chloro-2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-3-[(tetrahydro-2-furanyl)methyl]-4(3H)-quinazolinone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19ClN2O5S |
| Molecular Weight | 446.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 566188-43-0)
- 2-Chloro-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzenesulfonamide (CAS 866018-72-6)
- 3-(3-Chloro-2-methylphenyl)-N'-(4-methylbenzoyl)-4-oxo-3,4-dihydrophthalazine-1-carbohydrazide (CAS 866039-05-6)
- 3-(3-Chloro-2-methylphenyl)-N'-[(1E)-(3-methoxyphenyl)methylidene]-4-oxo-3,4-dihydrophthalazine-1-carbohydrazide (CAS 672949-04-1)
- 5-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethyl)-N-phenylthiophene-2-sulfonamide (CAS 861208-58-4)
- 5-(5-Chloro-2-methoxybenzenesulfonyl)-8-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 861207-45-6)
- Methyl 6-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[(E)-[(dimethylamino)methylidene]amino]-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate (CAS 321430-39-1)
- 2-Chloro-6-fluoro-3,4-bis((4-methoxybenzyl)oxy)benzoic acid (CAS 2637445-13-5)
Recommended Standards
- N-(7-Nitro-9H-fluoren-2-yl)formamide (CAS 6583-71-7)
- Brilanestrant (CAS 1365888-06-7)
- 5-(4-((2-Chlorobenzyl)oxy)phenyl)-N'-(2-hydroxybenzylidene)-1H-pyrazole-3-carbohydrazide (CAS 634897-22-6)
- Undecamethylcyclohexasiloxan-2-ol DISCONTINUED (CAS 141102-71-8)
- 1,3-Dichloro-4-iodoisoquinoline (CAS 1168136-15-9)
- 1-(Thiophen-2-yl)cyclobutan-1-amine (CAS 1247844-28-5)
- 2-(pyridin-2-ylmethyl)azepane (CAS 527674-23-3)
- Methyl 2,5-dibromothiazole-4-carboxylate (CAS 914347-25-4)
- 3,6-Dimethylpyrazine-2,5-dicarboxylic acid (CAS 43015-44-7)
- 2-((2-Aminoethyl)amino)isonicotinonitrile (CAS 1016521-67-7)
- 3-Amino-5-bromo-2-methylbenzonitrile (CAS 1000342-36-8)
- 2-(bis(propylthio)methylene)malononitrile (CAS 80596-43-6)
- 4-Amino-3-chloro-5-(trifluoromethyl)benzoic acid (CAS 95656-52-3)
- (Tyr?)-C-Peptide (human) (CAS 57327-90-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com