5-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethyl)-N-phenylthiophene-2-sulfonamide CAS 861208-58-4
| CAS No. | 861208-58-4 |
| Molecular Formula | C18H14ClF3N2O2S2 |
| Molecular Weight | 446.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethyl)-N-phenylthiophene-2-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethyl)-N-phenylthiophene-2-sulfonamide (CAS 861208-58-4), molecular formula C18H14ClF3N2O2S2 and molecular weight 446.89 g/mol, is a CATO reference standard with documented purity and traceability.
5-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethyl)-N-phenylthiophene-2-sulfonamide (C18H14ClF3N2O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H14ClF3N2O2S2 |
| Molecular Weight | 446.89 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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Recommended Standards
- 5-(4-((2-Chlorobenzyl)oxy)phenyl)-N'-(2-hydroxybenzylidene)-1H-pyrazole-3-carbohydrazide (CAS 634897-22-6)
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- Methyl 5-((3-chlorophenyl)carbamoyl)-2-(4-fluorobenzamido)-4-methylthiophene-3-carboxylate (CAS 335409-80-8)
- Brilanestrant (CAS 1365888-06-7)
- Sulfosuccinimidyl 3-(4-Hydroxyphenyl)propionate (CAS 106327-86-0)
- 1-Azetidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester (CAS 128117-22-6)
- <I>N </I>-Boc-serinol (CAS 125414-41-7)
- 6-Fluoro-1-methyl-1H-indazol-3-amine (CAS 171809-13-5)
- tert-Butyl N-[2-(3-hydroxypiperidin-1-yl)ethyl]carbamate (CAS 857637-25-3)
- 3-(Aminomethyl)-1h-indol-5-ol (CAS 52700-62-6)
- 2,2-Dipropylpropane-1,3-diol (CAS 24765-54-6)
- 4-Benzoyl-N-[3-(morpholin-4-yl)propyl]-1H-pyrrole-2-carboxamide (CAS 478040-12-9)
- trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride (CAS 366-93-8)
- Human glucagon CRS (CAS 9007-92-5)
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