Atrasentan Impurity 81 CAS 1058552-23-0
| CAS No. | 1058552-23-0 |
| Molecular Formula | C35H50N2O7 |
| Molecular Weight | 610.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Atrasentan Impurity 81 (CAS 1058552-23-0, C35H50N2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Atrasentan Impurity 81 (C35H50N2O7) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Atrasentan Impurity 81 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H50N2O7 |
| Molecular Weight | 610.79 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 75 (CAS 1058551-12-4)
- Atrasentan Impurity 82 (CAS 1058552-27-4)
- Atrasentan Impurity 108 (CAS 1059052-13-9)
- Atrasentan Impurity 109 (CAS 1059052-17-3)
- Atrasentan Impurity 134 (CAS 1058349-07-7)
- Atrasentan Impurity 144 (CAS 1058349-57-7)
- Atrasentan Impurity 153 (CAS 1058404-03-7)
- Atrasentan Impurity 66 (CAS 1058349-13-5)
Recommended Standards
- Peramivir Impurity 88 (CAS CATO-C4X-183388)
- Oxybuprocaine Impurity 9 (CAS CATO-C4X-12279)
- Peramivir impurity 143 (CAS CATO-C4X-1833143)
- Ethyl 1-(5-((4-chlorophenyl)sulfonyl)-4-(2,4-dichlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 956779-71-8)
- Sofosbuvir Impurity 25 (CAS CATO-C4X-105225)
- Solriamfetol Impurity 7 (CAS 178429-63-5)
- Norethisterone Acetate EP Impurity E (CAS 66964-58-7)
- 4-Formyl-3-hydroxy-N-(2-oxo-2H-benzo[d]imidazol-5-yl)-2-naphthamide (CAS 55447-62-6)
- 1,5-Dimethyl-2,5-dihydro-1H-pyrrole-3-carboxamide (CAS 92020-07-0)
- 4-Bromo-5-fluoro-2,3-dihydro-1H-inden-1-amine (CAS 1273676-81-5)
- N-(3-Hydroxy-3-phenylpropyl)cyclobutanecarboxamide (CAS 1396747-41-3)
- 5’-O-(4,4’-Dimethoxytrityl)-3’-β-hydroxythymidine (CAS 112501-53-8)
- (3-Aminopiperidin-1-yl)(2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzo[d]imidazol-6-yl)methanone hydrochloride (CAS 1652591-82-6)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com